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nicotinamide adenine dinucleotide

  • Dear Readers,

    Welcome to the December 2018 issue of TotalHealth Magazine.

    Charles K. Bens, PhD, “NAD—The Superstar For Cellular Healing.” Bens educates us on the role of NAD (nicotinamide adenine dinucleotide) a form of vitamin B acting as an enzyme that has been proven to be a key nutrient in preventing and reversing the cellular damage in the human body. Bens has includes several graphics, which helps to explain the role of NAD. And informs us of what symptoms may be involved if you have this deficiency.

    My New Plan To Reset Your Metabolism In Just 4 Days,” by Ann Louise Gittleman, PhD, CNS. Long-time weight loss, detox, and anti-aging expert shares some of the accolades received from readers of her new book “Radical Metabolism.” Many pleased readers have taken action based on the book.

    Gene Bruno, MS, MHS, “The Natural Treatment of Rheumatoid Arthritis.” If you are looking to reduce pain and promote healthy joints in those suffering from RA, Bruno has suggestions of natural supplements that may help lessen RA symptoms. O3FA (omega-3 fatty acids), Valerian and California poppy may help promote sleep and pain relief for arthritis sufferers. He suggests that the concurrent use of all of these natural substances may yield a better result than any one individually.

    Amy Shah, MD, contributes “OTC Pain Medication Mistakes And Cleaner Options.” This article is for all of us current and future shoppers at the over-the-counter medicine aisle. It can be summarized as a wake-up call to read the labels, know what all the ingredients are and how they may affect you whether combining with prescription drugs. Shaw advises all to talk to our pharmacist and consult with our doctors.

    Gloria Gilbère, CDP, DAHom, PhD, offers “Traditional Holiday Drinks From Ecuador, Colombia And Peru.” With the traditional holiday drinks recipes from Ecuador, Colombia, and Peru, Gilbère gives us a snapshot of what you might expect to experience when traveling to those South American countries during the holiday season. Gilbère suggests adapting the ingredients to fit our own holiday traditions.

    Shawn Messonnier, DVM, this month brings us Part 3 of “Arthritis In Pets.” The focus is on acupuncture. Our resident vet presents all the types of this therapy: Laser therapy, Aquapuncture, Implantation, Electroacupuncture, Moxibustion, and Acupressure. If your pet is showing signs of arthritis you’ll find this third in the series of value.

    Thanks to you our readers, the authors and advertisers who have all supported TotalHealth during the 2018 year. We wish all a Happy and Healthy Holiday Season!

    Best in health,

    TWIP—The Wellness Imperative People

    Click here to read the full December 2018 issue.

    Click here to read the full December 2018 issue.

  • Introduction: Our cells develop disease and premature aging due to every day assaults on our cellular health, such as:

    • Poor nutrition
    • High toxin levels
    • Poor sleep
    • High stress levels
    • Genetic predispositions
    • Under or over exercising

    Conventional medicine typically uses drugs and surgery to address these health challenges, however, these are usually not sustainable strategies. Treating symptoms and managing disease is not as valuable as preventing and reversing disease.

    NAD (nicotinamide adenine dinucleotide) is a form of vitamin B, acting as an enzyme that has been proven to be a key nutrient in preventing and reversing the cellular damage previously mentioned. This diagram depicts the five stages of cellular deterioration that could be delayed with the use of NAD.

    Markers of Cellular Deterioration
    As cells continue to experience these assaults on our cellular health, our bodies begin to produce recognizable markers of this deterioration, including:

    • Inflammation
    • Oxidative stress
    • Metabolic dysfunction
    • Symptoms of deficiency
    • DNA damage
    • Biochemical imbalances
    • Disease (heart disease, diabetes, cancer, etc.)

    Stages of Disease at the Cellular Level Charles K Bens

    Early Warning Health Assessment
    Cell replacement and survival become seriously compromised if these cellular reactions are not caught soon enough. Some good diagnostic tools that can provide some early warning protection include:

    • The glucose challenge test
    • Thermography
    • C-reactive protein
    • Homocysteine
    • Galectin 3
    • Vitamin D3 levels
    • Heavy metals levels
    • Omega 3/6 levels
    • NA/NADH ratio
    • Fibrinogen

    By using these early warning health assessment tools, it has been proven that natural/functional medicine doctors can prevent and reverse over 80 percent of all chronic illness, and the formula for this prevention and reversal process is usually the same in each case.

    1. Identify and remove toxins in the body.
    2. Adopt a Mediterranean style diet.
    3. Use moderate exercise, including aerobic, resistance and flexibility.
    4. Use quality nutritional supplements as needed.
    5. Practice meditation, yoga and other positive thought practices. Reduce stress as much as possible.
    6. Get good restorative sleep every night.

    The evidence-based science behind these natural approaches is indisputable and will eventually be adopted by everyone once the profit-driven health care system is dramatically changed. We need a health and prevention system instead of a disease management profit-based system.

    NAD Major Cell Protector

    NAD is now beginning to assume its role as the next superstar in this strategy to improve cellular health in some very serious ways. Here are the primary improvement categories for cellular health improvement identified in current NAD research.

    • Reduced levels of cellular inflammation (NF-KB).
    • Reduced levels of free radicals (oxidative stress).
    • Improved metabolic homeostasis (biochemical balancing).
    • Reduced cell cycle disturbances via ADP-ribose, polymerase (PA R P-1) and sirtuins (Sirt-1-7).
    • Repair of DNA damage in cell nucleus.
    • Improvement in cell mitochondria function (energy).

    The cell cycle process controls cell replacement and cellular death. If any of the key change junctures are negatively influenced by toxins, poor nutrition or stress of some kind, then this cycle could be disrupted, leading to the development of inferior cells, mutated cells or even cell death. NAD has the ability to correct these disturbances and even fix mutated DNA if it can be delivered to the cells before permanent mutation can occur.

    The Cell Cycle

    As We Age
    In addition to the impact of poor nutrition, toxins, and stress, there are also natural genetic and biochemical changes that happen as part of “normal aging.” Cellular replacement time declines, enzyme, probiotic and antioxidant levels decline, and, levels of NAD decline. We can address most of these cellular aging factors with better diet, detoxification, stress reduction and supplementation with key enzymes, probiotics, and other nutritional supplements, include NAD. This aging process, as related to the presence of NAD, looks something like this:

    1. NAD declines with age — The DNA in our cells becomes damaged due to assaults by free radicals. This increases the need for NAD, because it is a key element of the DNA repair process.

    2. NAD/NADH ratio — This decline in NAD can change the ratio of NAD/NADH, which causes disruption to the basic cellular processes it facilitates.

    3. Early cellular changes — Low NAD leads to decreased mitochondrial oxidation and insufficient ATP production. Low energy.

    4. Low energy consequences — Insufficient cellular energy impedes cellular function, including DNA maintenance and repair.

    5. Mitochondrial communication—Reduced mitochondrial communication impedes cellular defense mechanisms, such as immune function as well as increased vulnerability for microbial illnesses, genetic predisposition and biochemical imbalances. (Diabetes, heart disease, etc.)

    Increasing NAD levels
    The very first step in this effort to increase NAD levels is to get the NAD/NADH blood test. This will establish the existing levels of NAD homeostasis. Then, if levels are low or out of balance, the following steps can be taken:

    • Eat these foods high in NAD—Green vegetables, chicken, fish, crimini mushrooms, yeast, beer and dairy products (preferably goat products).
    • Take a good NAD supplement—One of the earliest products was developed by Life Extension Foundation, which contains the patented ingredient, NIAGENTM.

    The probable outcomes of increasing NAD levels:

    • Reduce inflammation
    • DNA repair
    • Increased energy
    • Improved immune function
    • Genome integrity
    • Damaged cell replacement
    • Reduced oxidative stress
    • Reduced aging stress
    • Decreased susceptibility to cancer.
    • Resolution of many heart disease challenges.
    • Reduced blood pressure due to improved arterial flexibility.
    • Improved function for early stage organ compromise.
    • Improved cellular preformation related to addiction issues.
    • Possible improvement in various brain related challenges, such as depression, anxiety and dementia.

    While we should be cautious about using the term ¡§miracle cure,¡¨ it is obvious that NAD plays a crucial role in our cellular health. We know that levels of NAD decline by as much as 50 percent between the ages of 40 and 50. We also know that this decline has a potentially negative impact on every one of our 60 trillion cells.

    • Free radicals cause damage to our DNA, which is a proven cause of disease, such as diabetes, heart disease, cancer and many brain-related illnesses.
    • NAD can protect our cells from the damage and, in some cases, can even reverse some of this damage. The science behind this is growing every day.
    • To achieve optimal health, we need to do many things, including taking quality nutritional supplements. There is no science to dispute this fact.
    • NAD should definitely be one of those supplements, and adding it is a wise decision.