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  • When skin is exposed to the sun, the body's protective mechanism against oxidative damage is an increase in skin pigmentation (i.e. increase in melanin production)—also known as getting a tan. In addition to the tan, however, a localized hyperpigmented lesion, also known as age spot, solar, or senile lentigo, may occur, especially in Asian and Caucasian populations.1 These benign-pigmented lesions are not only considered unattractive on visible areas of the skin, such as the face, hands, upper back and forearms, but they are also a marker for skin photo-damage (i.e. damage caused by the sun, leading to wrinkles, etc.).2,3